BioCeuticals Launches LDT for Improved Absorption, more Accurately Delivery of Active Ingredients [Interview][Transcript]

Belinda_Reynolds_BioCeuticals_liposomal_rangeGuest: Belinda Reynolds
Presenter: Wayne Bucklar
Guest Bio: Belinda Reynolds is the Education Manager at BioCeuticals. She graduated with an Honours Degree in Nutrition and Dietetics in 2003. She has been involved in the complementary medicine industry for nearly 15 years – 10 of these working for BioCeuticals as the Practitioner Sales Consultant, Team Leader, Presenter, Educator and Writer, with an involvement in Marketing and Product Development. Outside of this Belinda has spent time working in hospitals and lectured at the Australasian College of Natural Therapies. Belinda’s greatest passion is assisting practitioners in developing their knowledge by presenting new research in the area of integrative medicine. Now a mother of two, pre- and postnatal, infant and child health have evolved as subjects particularly close to her heart.

Segment overview: In today’s Health Supplier Segment, we welcome returning guest BioCeuticals‘ Education Manager Belinda Reynolds as she talks about the recent launching of their range of nutritional liquid supplements using liposomal encapsulation technology to improve absorption and more accurately deliver active ingredients. According to Belinda, liposomal delivery technology (LDT) is a cutting edge nanotechnology method of making microscopic “bubbles” to encapsulate various substances. She also said liposomes and nano-emulsions are very efficient because they allow dose levels to be smaller while still delivering effective ingredients.

Transcription

Health Professional Radio – BioCeuticals liposomal encapsulation technology

Wayne Bucklar: You’re listening to Health Professional Radio, today my guest is joining me from Australia. Her name is Belinda Reynolds and she’s the Education Manager at BioCeuticals. Belinda welcome back to Health Professional Radio.

Belinda Reynolds: Thank you very much, and thanks for having me.

W: My pleasure. Now Belinda today we will goanna have a chat about I guess a new delivery your technology certainly one that I haven’t heard of before, can you tell us about “Liposomal Delivery Technology” please?

B: Sure. So the Liposomal Technology itself has been around for a few decades but primarily the research in the area of Liposomal Delivery had focus on drug delivery and it’s only more recent that we’ve started to look at using liposome to deliver nutrients more efficiently into the body. And what a Liposomal Delivery Technology entail is basically tiny little vesicle, which almost encapsulate a particular nutrient. And that little vesicle is made up of a phospholipid bilayer, so really what it resembles a cell membrane around a nutrients, Chris Shade over in the State he developed a particular technology which enabled these liposomes to then be made into a really small size, so they’re now a nanoparticle size, which means that these encapsulated nutrients can pass possibly across the new… tissue of the mouth. So what it means is that we’re able to get nutrients into the body a lot more rapidly and we’re also bypassing the digestive system, so that is now removed any concerns which mean in the past associated with the potential bioavailability, of course someone may have had certain gastrointestinal issues.

W: So Belinda have I get this right, you don’t have to swallow these – they’re absorbed directly to the mucus in the mouth?

B: Yes, so generally what we recommend when someone is using a liposome, particularly with the Nano technology is that you hold the formula in your mouth for about 90 to a 120 seconds and that then allows that passive uptake and then you can swallow the rest. Some still will be absorbed by the digestive system later on, to that that isn’t absorbed through the mouth. But the best way and the fastest way to get the liposomal nutrients into the body is by holding it in the mouth and sort of pushing it around, so that there’s are the opportunity for them pass there and then.

W: Okay I have colleagues who have great difficulty even as adults swallowing tablets, this would work very well for them.

B: It would and I think that’s particularly a good area for the use of the liposomes as for those people that have had difficulty in the past swallowing tablet. The other area where they seem to be quite useful is for achieving greater dosages in the serum of certain nutrients, so there are certain conditions that require particularly high doses of certain nutrients in order to achieve a good clinical outcome, and the difficulty in the past has been that people may have this certain level of intestinal tolerance to a nutrient if they try and take too much, it really upsets their stomach. And also there’s a limit to what can be absorbed by the digestive tract, but now because we have this technology and that the nutrient is able to pass within these liposomes quite possibly across the mucus membrane of the mouth, it enables us to get a high dose into the body and then the course of the phospholipids are membrane or a layer around the nutrients, the liposomal will merge with the cell membrane of our own cells in the body and in a way deliver that nutrient directly into our cells. And then because the liposome structure is that small, they also pass possibly across the blood brain barrier as well as getting the nutrient into the body more rapidly and more efficiently. We’re also getting them up into the cells more effectively and also across the blood brain barrier more efficiently to the nutrients, if we wanted the nutrients to get into the central nervous system to act within the brain, that process is achieved more efficiently with the use of the Nano sized liposome.

W: I was fascinated to read this works with both water soluble and fat soluble biologically active substances, that’s a very neat trick.

B: Generally with your water soluble nutrients, the liposome around that nutrient will be a bilayer of phospholipids. So what is in the center of the structure is a water soluble environment, so nutrients such as vitamin C will be held there within that phospholipid bilayer. When it comes to a fat soluble nutrient the structure is what we’d refer to is a nano-emulsion. So it’s a single layer of phospholipids surrounding a fat soluble core, so that’s fatty acid tail which are actually hydrophilic of the phospholipid are pointing inwards interacting with the fat soluble nutrient in the center of the core so that would be for your say vitamin D3 and also Coenzyme Q10.

W: You mentioned D3 and you mentioned CoQ10, what are the products are in this delivery mechanism?

B: So yes doing the nano-emulsion we have the vitamin D3 and Coenzyme Q10 so they are the two fat soluble nutrients. And then in addition to that in regards to the water soluble nutrient that we have, which should be encapsulated in that phospholipid bilayer, we have a vitamin C, so liposomal vitamin C, a glutathione, and Lipoic acid and also a Methyl B-12, so an activated vitamin B12.

W: Now I know CoQ10 because I’m a personal fan of it myself, are these amounts small? Does this change the pricing of the supplement?

B: So generally when you look at how much you absorb from the supplement it does work out almost better value. But for example with Coenzyme Q10 per two sprays of the liposomal liquid you get 14 milligrams of Coenzyme Q10 and the increased uptake are in using the nano sized liposome, it will vary from person to person and from product to product and how long you hold it in your mouth and there’s a variety of different parameters and different practice which can alter how efficiently you do observe the nutrient. But generally certain studies have shown that a liposome on nutrient can be taken up into the cell into about 100 times more efficiently than a standard nutrient. But again it will depend on the nutrient itself so they’re actually getting up to the body more effectively so you’re ultimately getting more of it into your body, into your cell, across your blood brain barrier. So in actual affect let say they have better value, potentially that what you may have been using before, what’s interesting about the nano size particle well is that they’re able to avoid clearance from the body for about 10 times longer than a standard nutrient. So what that means is that the nutrient when you take it, it will stay in circulation for around 10 times longer than with a normal supplement meaning that you’ve got 10 times more time for it to be available for utilization. Say for uptake to the cell then and passage across the blood brain barrier and those sort of things so there is a number of difference factor which help contribute to the nano sized liposomal nutrient being more effective for certain members of the population.

W: Now Belinda because of the small child I had to take courtesy of my Grandmother cod liver oil of this spoonful and it tasted really awfull, if I’ve got to put this in my mouth are they gonna taste like cod liver oil ?

B: They won’t taste like cod liver oil, no. They’ll vary from product to product in what they taste like. So… self-containing compound, so you will have a slightly awful taste there but they have had essential oils added to them to improve their flavor, I won’t say that they’re a delicacy.

W: (Laugh)

B: But certainly, (Laughing) quite pleasant to use generally with this self-containing compound like it would be fine in the Lipoic acid, we do recommend that their kept in the fridge to minimize the taste, and also the smell that can come from them if they’re heated up so in order to sort of maintain those, that will gonna let the properties, we do suggest that they are kept in the fridge for that reason. But it’s been all essential oils that have been used to flavor the product. We don’t add any extra sugar or artificial flavors, so generally they’re not going to test like … but they’re certainly are quite pleasant to use.

W: Well, see that’s good news.

B: (chuckle)

W: Now it’s not that I’m entirely self-serving by I do like my medicine to taste good as well as work well.

B: Yes. So yeah, definitely is important for you to get a good compliance.

W: Now Belinda are you kind of expecting that this delivery mechanism will be a major shift in the market place? Do you think a lot of people will swap to it as a preference?

B: I think they will over time, there’s obviously different individuals will have different need, some people will prepare some certain delivery forms but I really think that as people start to see the results that they achieve with this type of dosage from it, they will move to it. I mean there will always be a person who just simply prefer the tablet and will stick with that, but generally with this more rapid uptake and increased uptake and better ability to access areas of the body which are certain nutrients have had difficulty accessing before, I think it will certainly start to be the dosage form of choice for a lot of practitioners.

W: I’ve been chatting today with Belinda Reynolds, the Education Manager BioCeuticals. Belinda how can people get in touch with you if they want to know more?

B: So you can go to BioCeuticals website which is www.bioceuticals.com.au and you can visit the Contact Us section, where we have our customer service email and also numbers there if you’d like to get in contact with us and ask any question.

W: Thank you for being with us today Belinda, it’s been a lovely having a chat.

B: Thank you, great to chat with you again.

W: If you’ve missed my conversation with Belinda Reynolds, the Education manager BioCeuticals the good news is we have a full transcript on our website. We also have an audio archive on YouTube and on SoundCloud where you can listen to the interview in full. All of those resources are available at the Health Professional Radio website www.hpr.fm. My name Wayne Bucklar, thank you for listening to Health Professional Radio.

 

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