Back to School with Pediatric Life-Threatening Allergies

Dr. Vivian Hernandez-Trujillo, a pediatric allergist, discusses potential challenges children with life-threatening food allergies may face as they return to school during the pandemic, recommendations for parents, teachers, and children, and options for treating severe food allergies such as an epinephrine auto-injector like kaleo’s AUVI-Q® (epinephrine injection, SP) which is the only compact epinephrine auto-injector with a voice instruction system that helps guide patients and caregivers step-by-step through the injection process and can be mailed directly to people’s homes – an ideal option for social distancing.

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Neuromyelitis Optica Spectrum Disorder (NMOSD) Clinical Trial Program

Dr. Kathleen Hawker, M.D., Group Medical Director, Neuroscience at Genentech discusses the recent FDA approval of Enspryng™ (satralizumab-mwge) and the findings from the clinical trial program for the treatment of adults living with anti-aquaporin-4 (AQP4) antibody-positive NMOSD, a rare disabling neurological disorder often misdiagnosed as multiple sclerosis. She explains the unique mechanism of action of IL-6 receptor activity (which is believed to be a clinical hallmark of NMOSD) and the novel recycling technology which allows for subcutaneous dosing every four weeks. 

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White Matter Free Water Biomarker for Alzheimer’s Disease

Dr. Maxime Descoteaux, Co-founder and CSO of Imeka, “the only company to combine diffusion and AI to map white matter integrity” discusses the use of white matter free water biomarker in Alzheimer’s disease and why scientists should change their focus from grey matter to white matter when it comes to evaluating Alzheimer’s disease.  He also comments on MRI’s analyzed from INmune Bio’s XPro1595Phase 1b Clinical Trial.

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COVID Patient Designed Breathing Machine to Help Others with Illness

Dr. Matthew Putman, Ph.D., co-founder, and CEO of Nanotronics, a science technology company, tells of his personal battle with COVID-19 and how he was inspired to create a bilevel positive airway pressure machine (BiPAP) device called nHale.  The device is designed for comfort and ease-of-use with the simplicity of one button. It’s designed for use in hospitals and other healthcare facilities, such as emergency care spaces for COVID-19 patients, prison infirmaries, and nursing care facilities.

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Advancements in Acute Myeloid Leukemia Treatment

Dr. Courtney DiNardo of the MD Anderson Cancer Center discusses the difficult to treat acute myeloid leukemia (AML).  She shares findings from the phase 3 VIALE-A study published in the “New England Journal of Medicine” (NEJM Aug 2020) that showed that venetoclax combination with azacitidine helped newly-diagnosed AML patients ineligible for intensive chemo, live longer without progression of their disease than with azacitidine alone and how this combination is potentially a “practice changing” advance in AML treatment.

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COVID-19 Pediatric Positivity Rate

There have been recent articles stating that nearly 100k children in the U.S. have tested positive for COVID-19 during the last two weeks of July.  Dr. Keith Meyer, Medical Director, LifeFlight® Neonatal and Pediatric Transport Services at Nicklaus Children’s Hospital who treats patients in the Pediatric Intensive Care Unit discusses what they are seeing in children with COVID-19, what they know, how children do not respond to the virus the same as adults, and what the recommendations are to parents.

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