J&J Vision – Next Generation Lens For Cataracts – TECNIS Synergy

Dr. Rajesh Rajpal, MD, Global Head of Clinical and Medical Affairs, Johnson & Johnson Vision discusses the launch and availability of their TECNIS Synergy™ in the United States and Canada. This next-generation presbyopia-correcting intraocular (PC-IOL) lens offers cataract patients the widest range of continuous vision, and best near vision among leading PC-IOLs, without the visual gaps seen with some multifocal technology. He talks about how this new next-gen lens was developed​,​ designed​,​ and the science behind it​, as well as other innovations in eye care solutions.​ 

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The Shift To Value-Based Care

Returning guest, Dr. Lucie Ide, MD, PhD, founder and CEO of Rimidi discusses why multiple point solutions in healthIT are only a temporary fix, how providers can integrate such solutions to achieve better health outcomes across their entire population of patients, and how combining remote patient monitoring (RPM), chronic care management (CCM), telehealth and patient reported outcomes (PROs) with clinical decision support solutions will further enable holistic care, and drive greater efficiency for staff. 

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89bio – Fighting A Growing Non-Alcoholic Steatohepatitis (NASH) Epidemic

As much of the world’s focus this past year has been on making progress in fighting off the COVID-19 pandemic, some remained focused on other raging epidemics that existed prior to the emergence of COVID-19 and continue to worsen over time.  For Rohan Palekar, CEO of 89bio, a clinical-stage biopharmaceutical start-up, the raging epidemic is non-alcoholic steatohepatitis (NASH) and he discusses how they haven’t allowed the pandemic or the failures of other NASH treatments to hinder their progress of developing a solution for NASH.  He talks about what’s on the horizon for 89bio, including plans for continuing the development of their lead candidate, BIO89-100 with the initiation of a Phase 2b trial for the treatment of (NASH). 

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New Data on Janssen’s TREMFYA For Psoriatic Arthritis Patients

Lead author, Dr. Philip Mease, MD, Director of Rheumatology Research at the Swedish Medical Center/Providence St. Joseph Health and Clinical Professor at the University of Washington School of Medicine, discusses new data from the Phase 3 DISCOVER-1 and DISCOVER-2 studies published in “The Lancet Rheumatology” (July 2021) on the efficacy of guselkumab on axial symptoms in patients with active psoriatic arthritis. Up to 70% of PsA patients experience axial symptoms. 

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Avadel Pharmaceuticals – New Data On Narcolepsy Treatment

Dr. Jennifer Gudeman, Vice President, Medical and Clinical Affairs at Avadel Pharmaceuticals discusses new clinical data from the pivotal phase 3 REST-ON clinical trial that was presented at the SLEEP 2021 Annual Meeting.  The investigational therapy, FT218, for the treatment of excessive daytime sleepiness and cataplexy in patients suffering from narcolepsy is currently under review at the FDA with a PDUFA target date of October 15, 2021.  She also talks about the current treatment landscape and the unmet need among patients for a differentiated treatment option.  

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Ashvattha Therapeutics – Potential COVID Treatments That Address Brain Inflammation

Dr. Jeffrey Cleland, Ph.D., Chairman, CEO and President of Ashvattha Therapeutics, a clinical stage biotech company discusses treatments that are in development to address inflammation of the brain caused by COVID.  They recently announced positive interim results on its ongoing phase 2 PRANA clinical study, which showed that OP-101, a novel hydroxyl dendrimer therapeutic, has the ability to successfully cross the blood brain barrier and suppress hyperinflammation.  The company is also developing a class of novel hydroxyl dendrimer therapeutics that they hope will become the future of targeted therapies and unlock new levels of patient care across oncology, ophthalmology, and inflammatory diseases.  

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