Author: healthprofessionalradio

Dr. John Lewis, Ph.D., CEO of Aegis Life, Inc., a spinout of Entos Pharmaceuticals, discusses the company’s goal of developing a novel DNA vaccine using its proprietary gene delivery technology, Fusogenix, in the fight against COVID-19.  The flexibility of Fusogenix may enable Aegis Life’s investigational DNA vaccine to target and deliver simultaneously the Spike (S) protein and the Nucleocapsid (N) protein intracellularly. This approach may maximize the potential of inducing a potent, durable, and balanced T cell response against COVID-19, in addition to having a strong neutralizing antibody response.

September is Blood Cancer Awareness Month and Dr. Caron Jacobson, MD, Clinical Director, Immune Effector Cell Therapy Program, Dana-Farber Cancer Institute discusses the blood cancers lymphoma and leukemia and CAR T therapies.

Pam Nisevich Bede, a registered dietitian from Abbott, a global healthcare company and leader in nutrition science, discusses how to get “nutrition strong” and prep our bodies to fight off illness with lifestyle tips.

Glen de Vries, co-CEO and co-founder of Medidata, the most-used platform for clinical trials around the world, shares insights from his new book coming out on September 14, 2020, titled “The Patient Equation: The Precision Medicine Revolution in the Age of COVID-19 and Beyond”.

Bryan Witherbee, CEO of Adarza Biosystems discusses ZIVA™, a label-free protein detection platform that can accurately test 100s of protein from a single drop of blood in a time and cost-efficient manner. While the initial launch of ZIVA was focused on biomarker detection in cancer, they have changed direction to assist in vaccine development and immunosurveillance following COVID-19 and they are now applying this technology in the quantification of SARS-CoV-2/COVID-19 antibodies and other upper respiratory pathogens.

Dr. Kendra Grubb, surgical director of the Emory Structural Heart and Valve Center in Atlanta discusses data from a national survey released by patient advocacy group Heart-Valve-Surgery.com and supported by Medtronic, of more than 3400 heart valve patients and caregivers about managing heart valve disease and how a return to “active living” is key in their treatment decision.  The findings from the survey were the impetus for the “Active Living” Initiative.

Dr. John Martin, CMO of Butterfly Network discusses Butterfly iQ, the world’s first handheld, single-probe, whole-body ultrasound system that is making ultrasound technology universally accessible and affordable.

Brian Culley, CEO of Lineage Cell Therapeutics, a clinical-stage biotechnology company, discusses the three cell therapy programs they currently have in clinical trials: OpRegen – a cell replacement therapy for the treatment of advanced dry age-related macular degeneration (dry AMD), OPC1 – a cell replacement therapy for the treatment of acute spinal cord injuries, and VAC2 – an allogeneic cancer immunotherapy for patients with non-small cell lung cancer (NSCLC). 

Dr. Vivian Hernandez-Trujillo, a pediatric allergist, discusses potential challenges children with life-threatening food allergies may face as they return to school during the pandemic, recommendations for parents, teachers, and children, and options for treating severe food allergies such as an epinephrine auto-injector like kaleo’s AUVI-Q® (epinephrine injection, SP) which is the only compact epinephrine auto-injector with a voice instruction system that helps guide patients and caregivers step-by-step through the injection process and can be mailed directly to people’s homes – an ideal option for social distancing.

Dr. Kathleen Hawker, M.D., Group Medical Director, Neuroscience at Genentech discusses the recent FDA approval of Enspryng™ (satralizumab-mwge) and the findings from the clinical trial program for the treatment of adults living with anti-aquaporin-4 (AQP4) antibody-positive NMOSD, a rare disabling neurological disorder often misdiagnosed as multiple sclerosis. She explains the unique mechanism of action of IL-6 receptor activity (which is believed to be a clinical hallmark of NMOSD) and the novel recycling technology which allows for subcutaneous dosing every four weeks.