Overcoming Obstacles in Neuroscience at Start of Pandemic

Dr. Dalia Moawad, MD, Executive Director & Disease Area Lead for Neurological Rare Diseases at Genentech discusses the three things her team learned during the pandemic from the launching of Evrysdi (risdiplam) the first at-home oral medicine for adults and children two months of age and older with spinal muscular atrophy (SMA).

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LinQ is a Safe and Minimally Invasive Solution to Treat SI Joint Pain

In up to 30% of people with chronic low back pain, the SI joint is the hidden source of the pain. SI joint pain is often misunderstood and misdiagnosed. Only 10% of people with SI joint pain receive the treatment and relief they need to pursue active and healthy lives. LinQ by PainTEQ is the only minimally invasive solution on the market backed by extensive clinical research that can provide immediate pain relief. This is how LinQ works

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First Patient in Landmark Clinical Study Evaluating Engineered Macrophages in Humans

Carisma Therapeutics, Inc. announced (March 2021) that the first patient has been dosed in the Phase 1 multi-center clinical trial for CT-0508, studying the potential of chimeric antigen receptor macrophages (CAR-Ms) for cancer immunotherapy, specifically in solid tumors.  Dr. Debora Barton, MD, Chief Medical Officer at Carisma is here to talk about this novel approach in gene-based therapy development, as it is the first time CAR–engineered macrophages are being studied in humans. CAR-T cell therapy has revolutionized how cancer is treated and revealed the power of gene-based therapies, and it has met challenges with solid tumors. Carisma’s novel approach to immunotherapy may uncover potential treatment options that aim to address the unmet needs of patients, who are battling hard-to-treat cancers. 

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Regaining Hope After An Overwhelming Year in the Pandemic

Licensed marriage and family therapist and certified grief and trauma counselor, Kara Bowman discusses her new book entitled “Heartbreak to Hope: Poems of Support for Grief and Loss”.  She talks about how the book can help guide people through their experiences of isolation, sadness, and grief. She advises some other ways to find effective methods for dealing with painful emotions and find the capacity to grow, heal, connect and find meaning.

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Publication of 20-Year Outcomes of Oncotype DX GPS Test

Returning guest, Dr. Eric Klein, Chairman of the Glickman Urological and Kidney Institute at Cleveland Clinic discusses new 20-year outcomes from a development study of the Oncotype DX Genomic Prostate Score® (GPS) test that was recently published in JCO Precision Oncology (March 2021).  The study highlights the role of the GPS test, the only genomic test for prostate cancer with 20-year outcomes, in assessing the risk of long-term distant metastases (DM) and prostate cancer-specific mortality (PCSM) for patients with localized prostate cancer. 

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How 1 Year of Social Distancing Practices Have Impacted Americans with Alcohol Dependence

Addiction specialist, Dr. Melissa Fritsche, discusses what she has observed firsthand within her private practice pertaining to the pandemic exacerbating symptoms of alcohol-related addiction. She also explains why the doctor-patient connection built through in-person engagement is difficult to achieve using telehealth only methods when working with people on a deeply personal recovery journey.

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