Can Stem Cells Help Fight Parkinson’s Disease?
Chinese scientists have discovered that ESCs (embryonic stem cells) have the ability to relieve the symptoms of Parkinson’s disease in monkeys. The findings was published in Stem Cell Reports.
Frequently Asked Questions
What is the main topic discussed in this episode of Health Professional Radio?
This episode covers important developments in healthcare, including updates on Therapy. Health Professional Radio brings you expert insights and analysis on the latest medical news affecting healthcare professionals and patients alike.
How can healthcare professionals benefit from this information?
Healthcare professionals can stay informed about the latest developments in Therapy and related fields, enabling them to provide better patient care. Staying current with medical news helps clinicians make evidence-based decisions in their practice.
Where can I find more information about Therapy?
For more detailed information, listen to the full episode on Health Professional Radio and visit hpr.fm for additional resources. You can also subscribe to our podcast for regular updates on healthcare news and expert interviews.
Scientists have previously proposed ESCs as a therapy for Parkinson’s disease, but there are still inadequate preclinical studies proving its effectiveness and safety, particularly within living organisms.
Professor Zhou Qi and Professor Hu Baoyang from the Institute for Stem Cell and Regeneration of the Institute of Zoology within the Chinese Academy of Sciences led this study. They took two years to examine the efficacy and safety of dopaminergic neurons taken from monkeys’ ESCs
Parkinson’s disease is associated with the loss of dopaminergic neurons.
The research team implanted a neurotoxin in the monkeys that can replicate the effects of Parkinson’s disease.
In addition, dopaminergic neurons were generated under current good manufacturing practice (cGMP) conditions through clinical grade human ESCs.
These cells were infused into the brains of neurotoxin-induced Parkinson’s disease monkeys after undergoing several quality tests.
Researchers euthanized the monkeys for examination after nine months. They used imaging methods fused with blood biochemical tests and immunohistochemical evaluation.
Results showed that the implanted cells didn’t display extreme tumor formation or proliferation. The cells also survived and further developed in vivo.
No immune rejection of the cells or other serious adverse events were reported.
The clinical-grade human ESCs can be a reliable source of cells for Parkinson’s disease treatment.
China is preparing to have its first ESCs-based Phase I/IIa clinical study on Parkinson’s disease. The results of this study can provide enormous support.
Medical Disclaimer
The information provided on this website is for general informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional for medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.
