Ayellet V. Segrè, PhD: Research Presented at Association for Research in Vision and Ophthalmology (ARVO) 2022

Dr. Ayellet Segrè, PhD, Genetic Biostatistician Assistant Scientist at Massachusetts Eye and Ear, and Harvard Medical School Assistant Professor of Ophthalmology discusses her recent research “Integrating Gene Regulation and Single Cell Expression with Genetic Associations Identifies Genes and Cell Types Contributing to POAG Risk and IOP.”    

Dr. Ayellet V. Segrè received her Ph.D. in Genetics and Genomics from Harvard University and did her postdoctoral training at Massachusetts General Hospital and the Broad Institute of Harvard and MIT on genetic and pathway analysis of complex diseases. In 2013, she joined the core team of the Genotype Tissue Expression (GTEx) Project at the Broad Institute, whose goal was to identify genetic variants that regulate gene expression (eQTLs) in a range of human tissues. As part of GTEx, Dr. Segrè led the computational production of the genotype data and the consortium’s efforts in integrating eQTL with GWAS data to gain biological insights on the causal regulatory mechanisms of complex diseases and traits. Since the Fall of 2017, Dr. Segrè is a member of the Faculty of Ophthalmology at Harvard Medical School, and an Assistant Scientist at the Department of Ophthalmology at Mass Eye and Ear, where she leads the genetic biostatistics and -omics efforts within the Ocular Genomics Institute.